Just as folds are important in the ancient art of origami, they are also vital for the function of many proteins. Mutations ...

Summary: A research team has uncovered a molecular “switch” that precisely regulates NMDA receptors, key players in brain communication, by blocking excitatory synapse overactivity. The proteins MDGA2 ...

Researchers discovered that CaV2.1 channels at synapses can adopt nearly 200 shapes based on electrical activity, effectively entering a “memory state” that weakens signal transmission. These brief ...

Neurotransmitter transporters limit spillover between synapses and maintain the extracellular neurotransmitter ... inhibitory and modulatory neurotransmitters glutamate, GABA, and dopamine. The ...

We found that the overproduction of hevin is capable of reversing cognitive deficits in aged animals by improving the quality of synapses in these rodents.” Astrocytes are large cells that ...