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Heterogeneous Hippo pathway (YAP/TAZ) activation in lung adenocarcinoma drives tumor progression by enabling ferroptosis ...
Excessive physical exercise, especially without adequate rest, can damage the human body in various ways. In severe cases, it ...
Chronic inflammation occurs when the immune system is stuck in attack-mode, sending cell after cell to defend and repair the ...
Harnessing the power of a metabolite produced in the kidneys and absorbed from certain foods can mimic the health benefits ...
A study by the Center for Redox Processes in Biomedicine (Redoxoma) led by Marilene Demasi from the Butantan Institute (São Paulo, Brazil) presents a valuable new experimental model for investigating ...
Chronic inflammation occurs when the immune system is stuck in attack-mode, sending cell after cell to defend and repair the ...
Oncogenic YAP accelerates S-phase entry by shortening G1, leading to replication stress and sensitivity to CHK1 inhibition.
Parasitic tapeworm larvae release glutamate and other excitatory molecules that can directly excite brain neurons.
Sigvotatug Vedotin is an ADC that targets integrin αvβ6-positive tumor cells. It has an engineered antibody that ensures high ...
The Best Protein Powder Overall: Optimum Nutrition Gold Standard Whey Protein Powder, $42 $36 The Best Tasting Protein Powder: Ghost Nutter Butter Protein Powder, $50 $41 The Best Value Protein ...
Proteins can be exploited to produce potentially highly specific drugs. Protein delivery methods must maintain bioavailability and activity of proteins and should not be toxic.
Novartis has been building a position in protein degraders - for example, signing a $1.3 billion alliance with Dunad Therapeutics in 2021 - but ARV-766 will be its first clinical-stage programme.