Scientists at UCL and the MRC Laboratory of Molecular Biology have recreated how RNA might have first replicated itself on ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

A new material developed at Cornell University could significantly improve the delivery and effectiveness of mRNA vaccines by replacing a commonly used ingredient that may trigger unwanted immune ...

Delhi has swapped scorching heat for sudden storms, with record-breaking rainfall and powerful winds disrupting daily life.

COVID-19 vaccine protection fades within months due to a lack of long-lived plasma cells. Booster shots restore some immunity ...

Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 ...

For decades, federal investment in research and development (R&D) has been the cornerstone of American innovation, fueling ...

While precision oncology requires robust biomarkers, current predictors for lung adenocarcinoma (LUAD) often show limited clinical utility. This study investigates the multifaceted roles of ZC3H12D, a ...

RBPs such as QKI and FUS enhance circRNA formation by facilitating the reverse splicing process. For instance, QKI's binding to precursor mRNA promotes circularization, while FUS interacts with ...

The scientists additionally turned their attention to the formation of the supercomplex in a situation, where the mRNA is defective. Normally, multiple ribosomes bind to a single mRNA strand ...

However, successful mRNA/LNP formation was achieved with helper lipids having relatively lower transition temperatures, such as DOPE, with a notable decrease in the transition temperature observed in ...

How do mRNA vaccines work? mRNA vaccines teach the immune system to target specific proteins, often proteins found on a pathogen, like a virus. To do this, they use instructions carried in a ...