Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big ...

Acyl carrier protein (ACP) plays a central role in fatty acid biosynthesis, acting as a molecular "shuttle" that carries, ...

Folate fortification of staple foods has ... as a tunable platform that allocates cellular resources for biosynthesis.” 1C pathways may act in the same way and fulfil functions as the TOR ...

Advances have been made by upregulating key enzymes in the folate biosynthesis pathway, but challenges remain due to species-specific responses and the complex interaction of folate with cellular ...

Purine biosynthesis de novo appears to increase ... Notably, serine donates one-carbon units for this process, taking part in folate metabolism. Many other metabolites in the cell that participate ...

1 Department of Chemistry, George Washington University, Washington, DC, United States 2 Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa Cofactor biosynthetic pathways ...

However, they show ATP depletion and accumulation of 5-aminoimidazole-4-carboxamide riboside 5′-monophosphate (ZMP; an intermediary of the novo purine biosynthetic pathway) when the culture medium has ...

serve as an excellent dietary source of folates for animals that lack the respective biosynthetic pathway. Unfortunately, the most important staple crops such as rice, potato and maize are rather poor ...