Current genetic strategies such as the one-hybrid assay 1 and phage-display techniques 2 suffer from the inability to detect proteins whose specific binding to a DNA element is dependent upon ...

Here we identify a high-affinity cocaine binding site associated with BASP1 that is involved ... removing its ATG start codon to create a FLAG-PDGF-TMD-BASP1 fusion protein. BglII-AsiSI restriction ...

The methyl-CpG-binding domain (MBD) proteins 'read' and interpret the methylation moieties on DNA, and thus are critical mediators of many epigenetic processes. Currently, the MBD family comprises ...

Discover the 9 heart-healthy foods that medical professionals eat daily to protect their hearts. Learn which foods boost ...

“Yummy yummy snacks jo hain protein se bharee ... can boost metabolism, enhance fat oxidation, and provide a strong dose of vitamin C, promoting immune function. Oats powder, high in beta-glucan (a ...

Vitamin D plays a classical hormonal role in skeletal health by regulating calcium and phosphorus metabolism. Vitamin D metabolites also have physiological functions in nonskeletal tissues, where ...

Liver-fatty acid binding protein (L-FABP) is found in high levels in enterocytes and is involved in the cytosolic solubilization of fatty acids during fat absorption. In the current studies, the ...

Our newly proposed, optimal workflow for structure-based generative design is shown to produce promising results, especially for those exploration scenarios, where diverse structures fitting to a ...

This paper describes the use of magnetic levitation (MagLev) to measure the association of proteins and ligands. The method starts with diamagnetic gel beads that are functionalized covalently with ...

Health conditions affecting fat absorption can significantly impact vitamin D status, as this fat-soluble vitamin requires proper absorption to reach circulation. Conditions like Crohn’s disease ...