Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, ...

Tiny fat bubbles carrying gene therapy have successfully repaired DNA in the lungs and liver of animals with alpha-1 antitrypsin deficiency—a promising leap toward treating humans with this rare ...

Researchers have uncovered hidden biological changes in fat tissue during weight loss, including cellular cleanup and energy-boosting recycling mechanisms. Scientists have, for the first time, closely ...

Presence of Different Ceramide Species Modulates Barrier Function and Structure of Stratum Corneum Lipid Membranes: Insights from Molecular Dynamics Simulations ...

SAN FRANCISCO, June 20, 2025 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for ...

The study reveals how ER-stressed adipocytes remotely regulate UPR activation in hepatocytes through the secretion of ceramide (Cer), a fat molecule that plays a major role in cell structure ...

A fat molecule consists of two main components: glycerol and fatty acids. Glycerol is an alcohol molecule with three carbon atoms, five hydrogens, and three hydroxyl (chemically bonded oxygen and ...

Mice lacking BCL6 had 40% less muscle mass than their healthy counterparts, and the muscle they did have was compromised both in structure and function.

Columbia researchers have found that a rare type of lipid is a key driver of ferroptosis, a form of cell death discovered by Columbia professor Brent Stockwell.