Apoptosis produced in B cells through Fas (APO-1, CD95) triggering is regulated by signals derived from other surface receptors: CD40 engagement produces upregulation of Fas expression and marked ...

We next analyzed whether Fas-mediated cell death in the presence of Fas-GPI still occurred via apoptosis. Fas-GPI transfected or control Jurkat cells were mixed at a 1 : 1 ratio with WR19L or 1A12 ...

Apoptosis was quantified by fluorescein isothiocyanate-conjugated annexin V/flow cytometric analysis and by DNA fragmentation. Fas expression was measured by flow cytometric analysis.

Scientists at UC Davis discovered a small genetic difference that could explain why humans are more prone to certain cancers ...

Scientists have made a novel discovery about how gene, "Fas-apoptosis inhibitory molecule", protects both immune and liver cells from programmed cell death. Scientists at Singapore's Bioprocessing ...

Introduction Substance P (SP) and its preferred receptor, the neurokinin-1 receptor (NK-1 R), are expressed in human tenocytes and this is particularly seen in the tenocytes in cases of tendinosis.

In support of this, cells carrying mutations in FasL, or its receptor Fas, were much less likely to undergo apoptosis when challenged with Aβ25-35. In addition, the researchers were able to show that ...

A new study has discovered a promising approach to improve the efficacy of adoptive cell therapies for cancer. The research, published in Molecular Therapy: Nucleic Acids, describes the development of ...

In our present work, we demonstrate for the first time doxorubicin-induced apoptosis in thyroid carcinoma cells and the Fas-mediated effects of this drug. Our study also demonstrated that ...

Singapore scientists have made a novel discovery about how gene, "Fas-apoptosis inhibitory molecule," protects both immune and liver cells from programmed cell death. Their research is published ...

Scientists at Singapore's Bioprocessing Technology Institute (BTI) have made a novel discovery about how the gene, "Fas-apoptosis inhibitory molecule" (FAIM), protects both immune and liver cells ...