Crohn’s disease (CD) is a chronic, progressive inflammatory bowel disease (IBD) that can affect any part of the gastrointestinal (GI) tract—from the mouth to the anus. It most commonly affects the ...

Our skin’s epithelial cells send electrical signals like neurons to cry out for help ...

A new study uncovers a surprising mechanism by which the SARS-CoV-2 virus, responsible for COVID-19, might cause immune-mediated tissue damage by targeting cells it has never infected.

Final results of POD1UM-201, a phase 2 study of retifanlimab, a humanized anti–PD-1 antibody, in patients with advanced or metastatic Merkel cell carcinoma (MCC).

Synopsis Ablation of RIPK1 in αβT cells results in spontaneous proximal small intestinal pathology, characterized by microbiome-mediated epithelial hyperproliferation and TNF-driven villus atrophy, ...

More information: Elnaz Ghotbi et al, Transcription factor KROX20 marks epithelial stem cell ancestors for hair follicle formation, Journal of Clinical Investigation (2024).

Small intestinal villi are projective microstructures from the mucosa that provide a large surface area for digestion and absorption. On the mucosa, intestinal epithelial cells undergo terminal ...

Scientists published more than three dozen papers as part of the Human Cell Atlas, an effort to map the human body cell by cell.

Find out what you need to know about the epithelium, including where epithelial cells are located in your body and how they affect your health.

Tourists visiting an unfamiliar city would have a hard time finding their way around if they were using nothing but a ...

How do bad bacteria find entry points in the body to cause infection? This question is fundamental for infectious disease experts and people who study bacteria. Harmful pathogens, like Salmonella, ...

Airway epithelial cells play an indispensable role in protecting the lung from inhaled pathogens and allergens by releasing an array of mediators that orchestrate inflammatory and immune responses ...