More information: Laura Martinez-Verbo et al, PVR (CD155) epigenetic status mediates immunotherapy response in multiple myeloma, Leukemia (2024). DOI: 10.1038/s41375-024-02419-z Provided by Josep ...

New epigenetic regulatory mechanisms involved in multiple myeloma growth. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2021 / 05 / 210517102627.htm ...

Several recent studies have highlighted the biological complexity of multiple myeloma (MM) that arises as a result of several disrupted cancer pathways. Apart from the central role of genetic ...

The epigenetic status of the PVR receptor might be a good prognostic marker for multiple myeloma, according to the latest research from the Cancer Epigenetics Lab led by Dr. Manel Esteller at the ...

Multiple myeloma is a type of blood cancer that appears mainly after the age of sixty. Its incidence, therefore, increases with the aging of the population. In this pathology, the bone marrow, the ...

A ground-breaking study has revealed crucial insights into the role of the histone methyltransferase NSD2 and its epigenetic target PKC-alpha in causing t(4;14) translocated multiple myeloma (MM ...

In the U.S., the average lifetime risk of multiple myeloma is less than 1%. In 2025, the American Cancer Society estimates that 36,110 new cases of multiple myeloma will be diagnosed, affecting ...

We diagnose multiple myeloma by doing blood, urine, bone marrow, and imaging tests. The disease can be classified as being “smoldering myeloma,” which is typically closely monitored, and “active ...

When you get a diagnosis of multiple myeloma, you may not even know what it is. Find out why this type of cancer is different from most others and what your treatment options look like.

More information: Laura Martinez-Verbo et al, PVR (CD155) epigenetic status mediates immunotherapy response in multiple myeloma, Leukemia (2024). DOI: 10.1038/s41375-024-02419-z Journal ...

The molecular pathogenesis of cancers, including multiple myeloma, is deeply related not only to genetic alterations but also to epigenetic changes. The epigenetic regulator KDM5 family proteins are ...

Multiple myeloma is a type of blood cancer that appears mainly after the age of sixty. Its incidence, therefore, increases with the aging of the population. In this pathology, the bone marrow, the ...