Our data indicate that interruption of the enterohepatic circulation of bile salts results in a relative bile-salt deficiency and a defect in the intraluminal phase of fat absorption. Four ...

THE enterohepatic circulation of bile pigment has been the subject of protracted debate. Recirculation of bilirubin, and its bacterial reduction products, the urobilinoids, has been postulated and ...

In hepatocytes, bile acids are secreted into bile canaliculi by bile salt export pump (BSEP), cholesterol ... up by hepatocytes enter the systemic circulation. Hepatocytes also efflux bile acids ...

They are absorbed and returned to the liver in the enterohepatic circulation. If the bile salt level in the portal vein rises (via the enterohepatic circulation), the production of bile salts in the ...

The five-year analysis showed that patients with PFIC2, also known as bile salt export pump (BSEP ... that surgical interruption of the enterohepatic circulation of bile acids can lead to ...

Thomas Horvath: Bile acids are cholesterol-derived compounds essential for digesting lipids and regulating metabolic pathways. They traverse a biochemical circuit known as enterohepatic circulation, ...

Excess intracolonic bile acid in diarrhea-predominant IBS results from alterations in the enterohepatic circulation of bile acids. Synthesis of bile acid is regulated homeostatically by feedback ...

Risk in Patients with Enterohepatic Circulation Disorders, Pancreatic Disorders, or Intestinal Disorders RELYVRIO contains taurursodiol, which is a bile acid ... has a high salt content.

In a healthy individual, enterohepatic circulation mediates ~95% of bile ... published reports that pruritus is initiated by retention of bile salts deposited in the skin. Notably, cholestyramine ...

and return to the liver through a process called enterohepatic circulation. When this process is disrupted due to overproduction of bile acids or issues in the ileum, bile acids leak into the ...