TRYVIO provides physicians with a therapeutic option targeting a previously unaddressed pathway.” TRYVIO is unique as it targets the endothelin system, an important pathway in hypertension’s ...

The major neurohormonal systems that are activated in HF are the renin-angiotensin system, the sympathetic nervous system, endothelin pathway, natriuretic peptides, and tissue necrosis factor ...

The drugs were started 24 h after infarction, as drugs can exert maximum benefits at this timing window. 17 The study duration was designed to be 4 weeks because the majority of the myocardial ...