Chronic kidney disease (CKD) is typically associated with severe fibrosis, the exact pathogenesis of which remains unclear.

Endothelial cells contribute to a subset of cardiac fibroblasts by undergoing endothelial-to-mesenchymal transition, but whether cardiac fibroblasts can adopt an endothelial cell fate and directly ...

Citation: Acetate controls endothelial-to-mesenchymal transition: Potential therapeutic target for reducing atherosclerosis (2023, June 19) retrieved 23 May 2025 from https://medicalxpress.com ...

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining ...

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells ...

Oncotarget published "Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth" which reported that the authors ...

The novel anthraquinone compound Kanglexin prevents endothelial-to-mesenchymal transition in atherosclerosis by activating FGFR1 and suppressing integrin β1/TGFβ signaling ...

Kobayashi, M., et al. (2022) Transforming growth factor-β-induced secretion of extracellular vesicles from oral cancer cells evokes endothelial barrier instability via endothelial-mesenchymal ...

Further experiments are needed to better understand endothelial cells’ transition to mesenchymal cells and how to control it. But given the critical role of the blood-CNS barrier, Zhu and Odelberg ...

The fact that mesothelial cells undergo epithelial-to-mesenchymal transition during continuous ambulatory peritoneal ... PETA-3 with α3β1 integrin localized at endothelial lateral ...

Methods: Experiments were performed in parallel on A549, H358 and 1437 NSCLC cell lines pretreated for 7 days using BMP7 or TGF-β, as well as control groups for comparison. All groups were maintained ...