Researchers at Texas Biomedical Research Institute and the University of Chicago have uncovered a mechanism that SARS-CoV-2, ...

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

Using cutting-edge cryo-electron microscopy, scientists at the University of Leicester ... Hexameric helicases are molecular machines powered by nucleotides that unwind DNA to start replication in all ...

have captured the initial steps of DNA replication, offering new insight into how cells accurately duplicate their genetic material, a process essential for life, growth, and reproduction. Using ...

Using cryo-electron microscopy (cryo-EM), a team of structural ... in cancer -- working to understand their influence on DNA replication. Additionally, the scientists unexpectedly captured for ...

Traditionally, scientists believed that early expression of a viral protein called large tumor antigen (TAg) by BKPyV drove kidney cells to replicate DNA, providing the necessary resources for viral ...

DNA replication is a tightly controlled process ... Using high-powered cryo-electron microscopes, Li, O'Donnell and their teams revealed previously unknown facets of the leading strand clamp ...

Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication ... Biology's Cryo-Electron Microscopy Facility ...

Abstract: Currently, one of the most effective techniques to study the mechanisms of DNA replication is using the electron microscopy. Typical imaging experiments result in terabytes of image data, ...

In this study, Qi Peng and colleagues used cryo-electron microscopy to determine a high ... a "forward sliding clamp" mechanism for DNA replication. The authors suggest that this finding could ...