Cryo-electron microscopy reveals hidden mechanics of DNA replication, sheds new light on cancer target Peer-Reviewed Publication. Memorial Sloan Kettering Cancer Center ...

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged. Cellular DNA is continuously exposed to both ...

“This work is a continuation of our long-standing research using electron microscopy to understand the mechanism of DNA replication, an essential function for every living cell,” explained co ...

Cdc6-Induced Conformational Changes in ORC Bound to Origin DNA Revealed by Cryo-Electron Microscopy. Structure , 2012; 20 (3): 534 DOI: 10.1016/j.str.2012.01.011 ...

The proteins that drive DNA replication—the force behind cellular growth and reproduction ... They then used an electron microscope at Brookhaven to pin down the exact structures at each ...

The researchers had already described in previous publications that DNA polymerase has its own repairer, an exonuclease, which allows it to correct errors that are introduced during DNA replication.

It’s the most famous corkscrew in history. Now an electron microscope has captured the famous Watson-Crick double helix in all its glory, by imaging threads of DNA resting on a silicon bed of nails.

The researchers developed new ways to release viral RNA replication complexes from cells and visualize them in sophisticated ways by cryo-electron microscopy (cryo-EM).

DNA replication is a tightly controlled process that copies the genetic code, ... Using high-powered cryo-electron microscopes, Li, ...

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged. Cellular DNA is continuously exposed to both ...

It may be why life is screwed up A tightrope of DNA between two silicon nanopillars It's the most famous corkscrew in history. Now an electron microscope has captured the famous Watson-Crick ...