A team of chemists has developed a new type of magnetic molecule that could be the key to storing vast amounts of data on absolutely miniscule drives.

Orforglipron is a small-molecule, nonpeptide glucagon-like peptide-1 (GLP-1) receptor agonist in clinical development for type 2 diabetes and weight management. Additional data on the efficacy and ...

Molecular structure of tuberculosis efflux pump reveals how bacteria resist key antibiotic by Jeff Hansen, University of Alabama at Birmingham ...

The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains. Experiments showed that the coiled-coil domain, whose predicted model extends from one of ...

Wegovy maker Novo Nordisk has hired the start-up Deep Apple Therapeutics to develop small molecules as its next weight-loss play.

The MIT model predicts molecular binding affinity at newfound speed and accuracy, offering a powerful tool for commercial drug discovery.

BioAge is rapidly advancing its internal small molecule APJ agonist program. In May 2025 the Company filed a U.S. provisional patent for a new class of orally active, chemically distinct apelin ...

A new way of thinking about Alzheimer's disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer's and other neurodegenerative diseases.

Researchers made small tweaks to the molecular structure of LSD to see if it could be turned into an effective brain-healing treatment.

Food contains more than 139,000 molecules, which influence nearly half the human proteome. Systematic analysis of food–chemical interactions can potentially advance nutrition science and drug ...

Drug Discovery How to choose a disease-fighting molecule Drugmakers sort through many modalities to find the best match for their target proteins by Laurel Oldach ...

Switching to tirzepatide linked to additional reduction in HbA1c, weight loss compared with escalating dulaglutide.