The single study finished enrollment of 47 patients with patients treated with Plinabulin, pembrolizumab and docetaxel on day 1 of each cycle until disease progression or intolerable severe adverse ...

Other Recently Approved Agents (eg, gemcitabine and docetaxel) Mechanism of Action: These are chemotherapy agents. Gemcitabine works by inhibiting DNA synthesis in rapidly dividing cancer cells, while ...

Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for ...

In a review published in the Journal of Dermatologic Science and Cosmetic Technology, two Chinese researchers looked into the mechanism of action of preservatives in cosmetics. Co-author Zhenyu ...

Figure 1: Mechanism of action of Bacillus Calmette-Guérin (BCG) and sequential Gemcitabine/Docetaxel (Gem/Doce) for the treatment of localized non-muscle-invasive bladder cancer Figure 2: Any-Grade ...

“We are encouraged by the results of this AD trial exploring how targeting the disease from different angles with different mechanisms of action impacts disease markers,” said Kreesten ...

A research team now describes a new mechanism of action that kills cancer cells through ferroptosis. In a first, a Bochum-based team has produced a substance capable of sending cancer cells into ...

today announced the publication of a peer-reviewed article in Frontiers in Immunology that enhances understanding of the molecular mechanism of action of sudocetaxel zendusortide (also known as TH1902 ...

Conclusions Pyrotinib, trastuzumab, and docetaxel showed superiority by significantly ... 1 2 The development of multiple anti-HER2 agents with various mechanisms of action has significantly improved ...

The mechanism of action of docetaxel involves the disruption of microtubule dynamics and interfering with cell division. This leads to apoptosis and cell cycle arrest. Docetaxel mainly targets ...

Plinabulin’s unique, immune-enhancing mechanism of action has a proven anti-cancer benefit that we believe will synergize with docetaxel and Keytruda and re-sensitize patients who progressed after ...