This discovery not only unveils a novel mechanism by which BAT influences liver metabolism but also highlights miR-206-3p as ...

Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...

The same deadly fungus is now being looked at as a potential cancer treatment. The therapy detailed in this new study is a ...

Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big impact on how well our cells absorb them, paving the way to more ...

This approach allowed a more comprehensive and less biased view of lipid diversity in marine plankton. The analysis showed that plankton lipid profiles are closely linked to their environment.

Scientists demonstrated a new cryogenic mass spectrometry approach for depth profiling frozen tiny lipid nanoparticles to reveal the layers and orientation of the constituent molecules. This method ...

Abstract We report on the aggregation and dynamic behavior of excipients in type I and surfactant-free lipid formulations containing water-soluble cosolvents. Specifically we have investigated the ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization and protein components of a lipid-transfer complex known as LPD-3 ...

Abstract Integral membrane protein structure determination traditionally requires extraction from cell membranes using detergents or polymers. Here, we describe the isolation and structure ...

Cationic nucleoside lipids (CNLs) derived from 5-nitroindole and 4-nitroimidazole bases were prepared from d-ribose by using a straightforward chemical synthesis. TEM experiments indicate that these ...

HANGZHOU, China-- (BUSINESS WIRE)--HighField Biopharmaceuticals, a clinical stage company using lipid-based therapeutics to treat cancer and other diseases, announced today publication of two ...

The findings also suggested that fructose promotes an inter-organ metabolic mechanism where liver-derived lipids support tumor growth, independent of direct fructose metabolism by cancer cells.