One of the main difficulties in studying dengue virus infection in humans and in developing a vaccine is the absence of a suitable animal model which develops the full spectrum of dengue fever, dengue ...

Monocytes/macrophages are important targets for dengue virus (DENV) replication; they induce inflammatory mediators and are sources of viral dissemination in the initial phase of the disease.

Histological and ultrastructural alterations in lung tissue of BALB/c mice infected with dengue virus serotype 2 (non-neuroadapted), by intraperitoneal and intravenous routes were analyzed. Lung ...

The CDC issued a health alert March 18 regarding dengue outbreaks in the Caribbean and the Americas. Dengue activity is high in parts of the U.S., and with the spring and summer travel seasons ...

As dengue spreads, researchers discover a clue to fighting the virus Scientists find protective T cells in children who experience two or more dengue virus infections Date: February 24, 2025 ...

Biological scientists have uncovered how the dengue virus uses its envelope protein to capture human plasmin from a blood meal to enhance the permeability of the mosquito midgut for infection.

Keywords: dengue virus, IRES, TP53, Mdm2, eGFP, Rluc, replication efficiency, GP160 Citation: Teramoto T (2025) Dual EMCV-IRES-integrated dengue virus can express an exogenous gene and cellular Mdm2 ...

Dengue is a disease with a high-impact on public health worldwide. Many researches have focused on the cell receptors involved in its pathogenesis. The role of soluble isoforms of DC-SIGN (Dendritic ...

The National Institutes of Health granted an IU professor $2.3 million for the research of the Dengue virus in September. Kay Choi, a professor in the Department of Molecular and Cellular Biochemistry ...