Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living ...

Given the amino-acid sequence or 3D structure of a protein, how much can we predict about its function using just a desktop computer? The recent explosive growth in the volume of sequence data and ...

Feb. 3, 2025 — Biological scientists have uncovered how the dengue virus uses its envelope protein to capture human plasmin from a blood meal to enhance the permeability of the mosquito midgut ...

When Alphabet announced in 2021 that its AlphaFold AI could predict the structure of almost every known protein, it was a major story, not just in the pharma world, but beyond.

The crystal structure of the core domain (N-terminal 30 kDa domain) of cytoskeletal protein 4.1R has been determined and shows a cloverleaf-like architecture. Each lobe of the cloverleaf contains ...

Review Article Published: July 2008 Interferon-inducible antiviral effectors Anthony J. Sadler & Bryan R. G. Williams Nature Reviews Immunology 8, 559–568 (2008) Cite this article ...

Influenza A virus (IAV) infection triggers derepression of host transposable elements (TEs), which have the potential to form double-stranded (ds)RNAs and could enhance innate antiviral immunity.

Proteins are the molecular building blocks and engines of the cell, and are involved in practically all life processes. Researchers at the Max Planck Institute of Biochemistry investigate the ...

In this work, simple and sensitive detection of dengue virus serotype-3 (DENV-3) antigen was accomplished by a one-dimensional (1D) HKUST-1-functionalized electrochemical sensor. 1D HKUST-1 was ...

Immunoprecise Antibodies Ltd. has discovered a highly conserved epitope across all four dengue virus serotypes (DENV-1, DENV-2, DENV-3 and DENV-4) using its proprietary Lensai platform powered by its ...

A cure for chronic hepatitis B requires eliminating or permanently silencing covalently closed circular DNA (cccDNA). A pivotal target of this approach is the hepatitis B virus (HBV) X protein (HBx), ...

Important factors governing NPs–protein interactions include the size (curvature), surface charge, and surface state of NPs as well as coexisting ions in solvents. In this study, we focused on the ...