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The enzyme developed in Arnold’s lab can create beta-lactam, gamma-lactam, and delta-lactam molecules. Credit: Caltech “In traditional synthetic chemistry, we have to tack extra reactive groups onto ...
In the 1990s, the lab of Frances Arnold showed how we can turn evolution to our advantage by manipulating microbes into evolving in a certain way. Now Arnold's team is using the technique to ...
Pigeons infiltrated the cabin of the Delta flight. Instagram/@cawtom. The pigeon, which was eventually captured, ...
Successful synthesis of gamma-lactam rings from hydrocarbons Date: March 1, 2018 Source: Institute for Basic Science Summary: Scientists have designed a novel strategy to synthesize ring-shaped ...
May 10 (UPI) --Scientists have developed a better way to build new antibiotics. Using a method known as directed evolution, researchers successfully synthesized beta-lactams, a molecular structure ...
Researchers have made a significant breakthrough in the field of asymmetric synthesis of beta-lactams, which are prominent in bioactive compounds. Their innovative approach employs nickel and ...
Successful synthesis of gamma-lactam rings from hydrocarbons With the help of computer simulations, IBS chemists have developed a novel reaction to insert nitrogen into C-H bonds and create useful ...
De-escalation of beta-lactam antibiotics was associated with a decreased risk of new resistance development compared with no change in beta-lactam antibiotic use, researchers found.
Patients who experienced allergic reactions after the beta-lactam challenge had them within 72 hours of admission, with four (2.2%) having reactions in an inpatient setting and one (0.5%) in the ED.
Many children with adverse reactions to beta-lactams are labeled as allergic without performing an allergy study to confirm it. In this retrospective study of 10 years, we detected only 3.3% ...