The fixed combination of the drugs dapagliflozin and metformin (trade name: Xigduo) has been approved since January 2014 for adults with type 2 diabetes in whom diet and exercise do not provide ...

Dapagliflozin 10 mg: 7.6% (dapagliflozin plus metformin XR) vs. 11.0% (dapagliflozin plus placebo) or 4.3% (metformin XR plus placebo) There were no major events of hypoglycemia.

Objectives: The efficacy of dapagliflozin as add-on therapy to metformin has been assessed in randomized trials. However, its effectiveness has not been assessed in a US real-world setting.

Signs, symptoms and other reports suggestive of genital infections were 14.8% (8.0% in men, 23.3% in women) with dapagliflozin added to metformin compared to 2.9% (0.4% in men, 5.9% in women) with ...

Doctors usually prescribe a medication called metformin as the first step in treating Type 2 diabetes. It helps lower blood ...

Bristol-Myers Squibb and AstraZeneca announced positive results from a Phase 3 study of dapagliflozin as add-on therapy to metformin for the treatment of type 2 diabetes. This 24-week, randomized ...

The studies showed that dapagliflozin in combination with metformin XR improved morning blood sugar (fasting plasma glucose, or FPG), had a higher proportion of patients achieving a therapeutic ...

Bristol-Myers Squibb and Astra Zeneca announced positive results from a Phase 3 study of dapagliflozin in adults with type 2 diabetes inadequately controlled on metformin monotherapy. The 52-week ...

Episodes of low blood sugar were less frequent in patients treated with dapagliflozin added to metformin than in patients treated with glipizide added to metformin In addition to sustained ...