Researchers have revealed the fundamental mechanisms underlying homologous recombination – one of the main DNA repair pathways in human cells.

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

In this article, we present and evaluate a parallelization strategy for implementing a local DNA sequence alignment algorithm. This strategy was implemented in JIAJIA, a scope consistent software DSM ...

We consider construction of a set of smaller 4 × 4 matrices to represent DNA primary sequences which are based on enumeration of all 64 triplets of nucleic acids bases. The leading eigenvalue from the ...

Researchers utilized recently published telomere-to-telomere genomes of humans, chimpanzees, bonobos, gorillas, and two orangutans to predict where DNA sequences might form alternative structures ...

On the one hand, it present the two-character alignment, improve the scoring function and scoring ... and experiment with simulated data which is randomly generated. When the length of DNA sequences ...

This process is divided in two phases. First, similarity regions between the long sequences are 2. Smith-Waterman's Algorithm for DNA Se-found with a local alignment algorithm. Second, for each quence ...

Researchers at the Centre for Genomic Regulation (CRG) created an AI tool which dreams up DNA regulatory sequences not seen before in nature. The model can be told to create synthetic fragments of ...

Contributed by Y. M. Dennis Lo, November 23, 2018 (sent for review September 13, 2018; reviewed by Michael R. Speicher and Alain R. Thierry) ...

Department of Polymer Science and Engineering, Hefei National Research Center for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei 230026, China Department of ...