G-quadruplex (G4) DNA is a stable secondary structure held together by G-G base pairs. DNA sequences capable of forming G4 DNA in vitro (G4 motifs) are enriched in ribosomal DNA and promoter ...

More information: Sophie Hertel et al, The stability and number of nucleating interactions determine DNA hybridization rates in the absence of secondary structure, Nucleic Acids Research (2022).

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

RNA strands are shorter than DNA strands. RNA sometimes forms a secondary double helix structure, but only intermittently. DNA is a much longer polymer than RNA. A chromosome, for example, is a single ...

The parent strand and the new strand then re-coil into the usual double helix structure. While DNA is exposed in a single-stranded form, certain sequences can fold into unusual DNA secondary ...

At the heart of the new detection system is the transition of DNA secondary structure from the native, right-handed "B" form to the alternate, left-handed "Z" form. "We found that the ...

Environmental factors can influence how these mutated genes manifest. Damage to the structure of DNA can occur in various ways. This includes when: Diseases or health conditions can result from ...

Her colleague Maurice Wilkins was independently pursuing DNA’s structure, and she had grown so miserable there, largely because of their rivalry, that she had found a position at another university.

A piece that aired on NPR this week about the discovery of DNA's structure neglected to mention the significant contribution of Rosalind Franklin to that scientific milestone. And now some ...