DNA Strand Mismatch Repair During the process of DNA replication, errors can sometimes occur. Nucleotide bases may be inserted, deleted, or mismatched into the DNA strand incorrectly. For this ...

Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. So why didn't Meselson and Stahl finally explain this mechanism until 1958 ...

For example, I would like to know where on each chromosome the process of DNA replication begins. Error-free duplication of DNA is essential for producing healthy cells. When this process is ...

DNA replication is the name given to this duplication process, which enables an organism's genetic information — its genes — to be passed to the two daughter cells created when a cell divides.

Scientists reported a novel molecular mechanism for the regulation of PCNA cycling during DNA replication. They proved that ATAD5-RLC opens PCNA ring to be removed from DNA as a bona-fide PCNA ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues ...

The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from ...

Mitochondrial DNA replication is a post-mitotic process that occurs throughout the organism’s lifetime. As mentioned earlier, mitochondrial DNA is organized into nucleoids containing various ...

Failures in DNA replication can lead to cancer, birth defects or other harm Video shows single pieces of double-helix DNA being copied Single-molecule view gives new insights into this process ...