Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have ...

Life is thought to have begun when RNA began replicating itself, and researchers have got close to achieving this in the lab ...

Additionally, the scientists unexpectedly captured for the first time a detailed picture of how the "engine" driving the cellular replication machinery moves along DNA in human cells. Their ...

By knocking out TEFM, they observed a notable reduction in mtDNA copy number, alongside a decrease in 7S DNA levels and strand-asynchronous replication intermediates. These findings suggest that TEFM ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their ...

The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from ...

But Surman points out that there are limitations to the self-replication; specific DNA chains are required as raw material for the process to work, as well as certain organic molecules ...

Researchers have gained a clearer insight into how common alterations to the structure of DNA affect the process of DNA replication. These structural changes can put a stop to replication, causing ...

Researchers have gained a clearer insight into how common alterations to the structure of DNA affect the process of DNA replication. These structural changes can put a stop to replication, causing ...

How skin cancer virus outcompetes DNA replication in host cells: Study(Shutterstock) The work, which was published today in the journal PNAS, gives insight on the fundamental topic of how viruses ...