University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their ...

A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.

At some point, RNA must have replicated itself before the evolutionary arrival of DNA and proteins, and now we might know how ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

Researchers unveil the fractal globule structure of DNA, providing new insights into genome organization and its implications ...

Methods The DIagnostic AngioGRAphy to find vascular Malformations (DIAGRAM) study (n=298; 69 macrovascular cause; 23%) is a prospective, multicentre study assessing yield and accuracy of CT ...

Cells are the smallest units of life. But even within the same tissue or organ, they are not all identical. New variations arise continuously during cell proliferation. While genetic mutations alter ...

If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally segregated, leading to genetic ...

This study finds these bacteria as the first example of an organism using ADP-ribose modification of DNA as a mechanism for regulating gene transcription and cellular replication. The ...

Precise replication of genetic material is essential to maintain genome stability. DNA replication is a tightly regulated process that ensues faithful copies of DNA molecules to daughter cells during ...