Scientists have documented the way a single gene in the bacterium that causes bubonic plague, Yersinia pestis, allowed it to survive hundreds of years by adjusting its virulence and the length of time ...

Scientists have documented the way a single gene in the bacterium that causes bubonic plague, Yersinia pestis, allowed it to ...

Researchers at the Max Planck Institute for Evolutionary Anthropology have addressed a longstanding challenge in CRISPR ...

It implements a probabilistic thermodynamic model that integrates DNA binding motifs (PWMs), methylation state, and binding logic using efficient forward-backward algorithms, SGD, and MCMC.

Find more information on the Altmetric Attention Score and how the score is calculated. Small-molecule inhibitors of DNA repair pathways are being intensively investigated as primary and adjuvant ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Find more information on the Altmetric Attention Score and how the score is calculated. Uracil-DNA glycosylase (UDG) is an important base excision repair (BER) enzyme responsible for the repair of ...

In the largest clinical genomic profiling study of non-Hispanic Black men with metastatic prostate cancer to date, ...

Ancestry and lifestyle choices of parents may affect the rate and type of new genetic changes that arise in their children, ...

Discover how nighttime wakefulness triggers DNA damage, metabolic chaos, and brain deterioration that accelerates aging and ...

The model then predicts which combination of DNA letters (A, T, C, G) are needed for the gene expression patterns required in specific types of cells. Researchers can then chemically synthesise ...