Researchers uncovered unexpected patterns of mutation inheritance in ... "We have identified forms of DNA damage that manage to escape our DNA repair mechanisms and persist in the genome for ...

They carry genetic instructions from DNA to ribosomes—the factories ... The graphs highlighted major differences in repair patterns, depending on the DSB position. This mathematical approach ...

How do DNA repair mechanisms detect and repair damaged DNA, and what happens when they fail? Defects in DNA repair underlie a number of human genetic diseases that affect a wide variety of body ...

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually. By 2050, the World Health Organization estimates it could surpass cancer and heart disease ...

Cells are then allowed time to recuperate before their DNA is extracted and resolved by PFGE. When cells are allowed time for repair, the original band pattern, instead of the smear associated ...

Using CRISPR technology, scientists uncovered genes that control C-A-G genetic stumbles in Huntington's disease ...

They found that the most common pattern was for the activity to be the same at all three observational points, whether the enzymatic period was during exonuclease repair or DNA extension. “This ...

Researchers uncovered unexpected patterns of mutation inheritance in ... "We have identified forms of DNA damage that manage to escape our DNA repair mechanisms and persist in the genome for ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

For this reason, they are at greater risk of accumulating damage and must develop alternative repair pathways to avoid dysfunction. Scientists do not understand how neuronal DNA damage is ...

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually. By 2050, the World Health Organization ...