Up to this point, we didn’t believe there was any other lineage that would appear in South America,” said archaeologist Andre ...

The latest imaging method from the Broad Institute uncovers structural disruptions in the nucleus associated with progeria at ...

Researchers at the Max Planck Institute for Evolutionary Anthropology have addressed a longstanding challenge in CRISPR ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

Upon irradiation, these molecules yield DNA interstrand cross-links under anaerobic conditions. The respective nucleotide triphosphates are substrates for some DNA polymerases. ICLs are produced upon ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

Contribution from the Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232, Department of Chemistry and Biochemistry, Concordia University, Montreal, ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor ...

Figure 1: Mechanism of nucleotide excision repair and base excision repair. The protein factors that are required for TCR and general genome repair (GGR) of DNA damage fall into two broad groups.

The pair really had figured out something very close to that. Working out the famous double helix structure of DNA was an achievement which led to countless advances and solved a mystery which had ...

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...