GPNMB-positive cells exhibit a pro-metastatic phenotype and are enriched in metastatic sites, suggesting a potential role for quiescence in tumor dissemination. Our findings position GPNMB as a ...

CHICAGO — A 14-gene molecular assay could help predict which patients with early-stage non-small cell lung cancer will benefit from adjuvant chemotherapy, according to results of the AIM ...

During the oral presentation “Cell Mimics As High Precision Controls for CGT Analytics and Potency Assays” Robyn Hall, Ph.D., Cell Therapy Specialist at Slingshot Biosciences, will highlight ...

Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.

Finally, we demonstrated that when cells were transferred from IKVAV-deficient to IKVAV-rich hydrogels, the hydrogel induced cellular dormancy was reversible. Collectively, our findings provide ...

Insights into the many facets of cell death, particularly cancer cell evasion mechanisms, are therefore critical to unlock new avenues for treatments. Agilent presents a fully automated, kinetic ...

Dronc’s function in regenerative proliferation after necrosis appears to be distinct from the mechanisms by which apoptosis might drive cell division, suggesting that Dronc can control regenerative ...

Multispan offers consistent, physiologically relevant cell assays that can deliver more reliable data.

PURPOSEMerkel cell carcinoma (MCC) is an aggressive skin cancer with a 40% recurrence rate, lacking effective prognostic biomarkers and surveillance methods. This prospective, multicenter, ...

ERBB2 is a member of the tyrosine kinase receptor family, a major cancer driver, and a recognized therapeutic target in many cancers, most importantly breast cancer. Its presence in soluble form in ...