They proposed a Cu(II)-bound OCR as a key intermediate for the hydrogen atom abstraction (HAA), which behaves like an active site of a copper-based enzyme both structurally and functionally.

A pair of recent papers helps clear up a longstanding mystery about the enzyme particulate methane monooxygenase (pMMO). The enzyme sits in the membranes of bacteria that consume methane as their ...

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Controversy has raged over the identity of the metal cofactor of membrane-bound methane monooxygenase, a methane-oxidizing enzyme. A study suggests that the answer is a cluster of two copper ions.

ATP7A typically resides in the cell's trans-Golgi network -- a sort of bus station inside the cell that sends new proteins out where needed -- where it delivers copper to enzymes that need the ...

That’s because copper plays an important role in brain function and development. Copper is used by enzymes that help supply energy to the brain, aid the brain’s defense system and relay ...

Peptides are known in the scientific community as glycyl-L-histidyl-L-lysine (GHK), which can easily bind with copper enzymes. Since the symbol for copper on the periodic table of elements is Cu ...

Exploiting the deficiency of a copper enzyme, dopamine-β-hydroxylase, we prospectively evaluated the diagnostic usefulness of plasma neurochemical levels, assessed the clinical effect of early ...

i.e. various copper enzymes." An important environment through which copper ions are transported in the body is blood. The primary function of blood is to transport molecules and ions from the ...

Faulty regulation of copper levels in tissues plays a major role in a wide range of illnesses, including Alzheimer’s disease, Parkinson’s disease, and motor neuron disease. An investigation of ...