They proposed a Cu(II)-bound OCR as a key intermediate for the hydrogen atom abstraction (HAA), which behaves like an active site of a copper-based enzyme both structurally and functionally.

That’s because copper plays an important role in brain function and development. Copper is used by enzymes that help supply energy to the brain, aid the brain’s defense system and relay ...

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Peptides are known in the scientific community as glycyl-L-histidyl-L-lysine (GHK), which can easily bind with copper enzymes. Since the symbol for copper on the periodic table of elements is Cu ...

ATP7A typically resides in the cell's trans-Golgi network -- a sort of bus station inside the cell that sends new proteins out where needed -- where it delivers copper to enzymes that need the ...

Controversy has raged over the identity of the metal cofactor of membrane-bound methane monooxygenase, a methane-oxidizing enzyme. A study suggests that the answer is a cluster of two copper ions.

A pair of recent papers helps clear up a longstanding mystery about the enzyme particulate methane monooxygenase (pMMO). The enzyme sits in the membranes of bacteria that consume methane as their ...

Faulty regulation of copper levels in tissues plays a major role in a wide range of illnesses, including Alzheimer’s disease, Parkinson’s disease, and motor neuron disease. An investigation of ...

1). Proteins called copper chaperones 7 then bind and transport Cu(I) ions to either cytosolic enzymes or to membrane transporters 8,9 that transfer Cu(I) ions into the organelles for copper ...