The findings provide insight into which patients may have favorable or inferior responses to immunotherapy for small cell ...

a new study led by Stanford University scientists suggests that a patient's response to immunotherapy may hinge on how immune cells cluster around tumors. Their results reveal that spatial ...

Aim: Few studies have compared cluster immunotherapy and conventional administration regimens. The aim of this study was to establish the safety profile of these different regimens in patients ...

The precise use of immunotherapy agents in locally advanced head and neck squamous cell carcinoma has not been clearly delineated, even in phase 3 trials. Although immunotherapy has emerged as an ...

Spatial transcriptomics on human brains parsed microglial reactions to amyloid immunotherapy. Both a vaccine and a therapeutic ... Van Olst pinpointed one cadre of genes, dubbed cluster 3, that ...

Immunotherapy agents targeting these molecules ... CD8+ T cells in the heart localized only to the CXCR3hi CD8+ T-cell cluster (Figure 3J). Importantly, the mice that were treated with CXCR3 blockade ...

This study compared the safety of subcutaneous immunotherapy (SCIT) using index-of-reactivity-standardized allergen extracts administered by means of a 4-week cluster titration schedule (cluster ...

"IL-12 has a lot of potential for cancer immunotherapy, but dosing it effectively ... "By sending labor-intensive tasks to the data cluster, we could run tests and validate results faster ...

In glioma immunotherapy, a hybrid “cluster bomb” nanovaccine with a high antigen loading capacity on a zinc oxide (ZnO) surface acted as a stimulator of dendritic cells (DCs) and activated T cells.

About 30% of lung cancer patients are accessible to targeted therapy or immunotherapy based on the current criteria. In this study, a novel gene cluster expression analysis was introduced with a ...