A Hong Kong University of Science and Technology (HKUST) research team has developed a catalytic enantioselective type II ...

Thus, developing a chemical synthesis reaction that selectively produces one enantiomer of chiral molecules useful in medicine is of great significance in the synthesis of drugs and their precursors.

Enantiomers, or molecule pairs that are mirror images of each other, make up more than half of FDA-approved drugs in use ...

Chirality is a critical factor in the discovery of drugs derived from natural products. Natural products are intricate organic molecules biosynthesized by living organisms, exhibiting a broad spectrum ...

Scientists have developed a novel technique that can produce pure therapeutic drugs without the associated side effects. Scientists from Hong Kong Baptist University (HKBU) have developed a novel ...

Scientists at The Scripps Research Institute (TSRI) say they have invented a new technique for constructing chiral drug molecules, whose structural complexity allows them to have mirror-image ...

Chiral molecules are those whose structural complexity allows them to have mirror-image, "left-handed" and "right-handed" forms. For drug molecules, usually only one of those forms works - the ...

One prominent example of a chiral switch occurred in 2001, when the US Food and Drug Administration (FDA) approved AstraZeneca’s esomeprazole (Nexium), a proton pump inhibitor (PPI) used to ...

Nearly 56% of all modern drugs and medicine are chiral in nature, and about 90% of those are a mixture containing equal amounts of two enantiomers of a chiral compound. Researchers often face the ...

The relevance of chiral technology is particularly pronounced in the pharmaceutical industry, where the different enantiomers of a drug can have different therapeutic effects or side effects.