In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a ...

Vildagliptin (VIL) is an antidiabetic drug that inhibits dipeptidyl peptidase-4 (DPP4) through a covalent mechanism. The molecular bases for this inhibitory process have been addressed experimentally ...

Researchers report that some disposable vapes released higher amounts of metals and metalloids than older refillable e-cigarettes and traditional cigarettes.

Scientists have mapped the molecular structure of glutamate receptors in the cerebellum for the first time using cryo-electron microscopy.

One of the few new diabetes medications that can be administered orally, vildagliptin seems effective at lowering glycosylated hemoglobin, fasting plasma glucose, and prandial glucose levels.

Here we report the molecular structure of this most prevalent Aβ40 fibril polymorph, determined with electron microscopy methods. Unique structural features of this polymorph may allow the future ...

Molecular structure of tuberculosis efflux pump reveals how bacteria resist key antibiotic by Jeff Hansen, University of Alabama at Birmingham edited by Sadie Harley, reviewed by Robert Egan ...

The structure showed 12 transmembrane helices in two pseudo-symmetric bundles and two periplasmic subdomains. Experiments showed that the coiled-coil domain, whose predicted model extends from one of ...

The U.S. Congress is in the thick of its crypto efforts this week, with the Senate starting on final votes to approve its first-ever crypto bill.

MIT and Recursion have released Boltz-2, the first biomolecular co-folding model that simultaneously predicts molecular structure and binding affinity with remarkable accuracy, approaching that of ...

The MIT model predicts molecular binding affinity at newfound speed and accuracy, offering a powerful tool for commercial drug discovery.

Researchers have discovered three compounds with anti-aging properties produced by a bacterium in the blood, which reduced damage and inflammatory responses.