Peptides are biomolecules formed ... such as Alzheimer's and Parkinson's, since after chemical modification the molecule acquires an amyloidal structure, which favors aggregation of molecules ...

A molecular reinterpretation of Alice in Wonderland reveals an ancient protein with a surprising function. In a ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

The central dogma of molecular biology is that the one-dimensional ... fold into the complex three-dimensional (3D) protein structures that have been solved at great expense experimentally.

In a paper published recently in ACS Nano, Lew and colleagues outline how they used the Nile red chemical probe ... visualize the fiber structures formed by synthetic peptides and by amyloid ...

chemical compounds that can interact with one another in many ways to take on an enormous number of possible three-dimensional shapes. Figuring out a single protein’s structure, or solving the ...

Most of those 20 have distinctive chemical properties ... into a complex three-dimensional structure. That structure is essential for the protein's function. Typically, figuring out the structure ...

This protein structure is part of a huge molecular structure in the human body. More than a thousand proteins form a pore through the membrane surrounding the cell nucleus. Almost two decades ...

“Protein structure prediction with AlphaFold2 caused ... Carroll, president of the American Chemical Society. “The fact that neural networks were used by Hassabis and Jumper is another example ...

such as secondary structure prediction, homology modeling, protein threading, ab initio methods and artificial intelligence (AI) methods. Structural biology is essential in the field of drug discovery ...

Through simulations and detailed analyses of the physical forces and chemical interactions involved ... study investigating the divergent structure of protein-regulated multiphase condensates ...