Landmark trials have shown that GLP-1 receptor agonists, originally developed for diabetes and weight loss, also provide ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

Mechanical stress can strongly influence the capability of a protein to aggregate and the kinetics of aggregation, but there is little insight into the underlying mechanism. Here we study the effect ...

Accurate extraction of molecular representations is a critical step in the drug discovery process. In recent years, significant progress has been made in molecular representation learning methods, ...

MIT engineers have developed a tiny implantable device that could revolutionize emergency treatment for people with Type 1 ...

The crystalline sponge (CS) method enables X-ray structural analysis without the requirement of crystallization of the target compound. However, several technical and crystallographic challenges, such ...