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UBC Okanagan researchers have developed a 3D bio-printed model that closely mimics the complexity of natural lung tissue, an ...
D bioprinting uses living cells as "ink" to create functional tissues. Discover how this technology is transforming medicine ...
Investigating chromatin's 3D architecture reveals its influence on gene regulation, shedding light on mechanisms underlying ...
Molecular glues, tiny molecules that connect one protein to another, are promising targets for pharmaceutical research. By ...
There are more than 100,000 people on organ transplant lists in the U.S., some of whom will wait years to receive one – and some may not survive the wait. Even with a good match, there is a ...
The first low-resolution structure, aided by docking with AlphaFold2, the artificial intelligence protein structure prediction system, showed the domain that spans the inner membrane of M.
The researchers then used cryo-EM to visualize the 3D structure of the RNA polymerase in this active, RNA-bound state at molecular resolution.
“We are finding the 3D structure of the genome,” said Satoshi Namekawa, PhD, professor of microbiology and molecular genetics at the University of California, Davis, and senior author of one ...
As for chromatin 3D structure, BMI1s have been reported to maintain the compartment domains (CDs) generally, but the mechanism by which they function remains elusive.
Structure’s lead amylin-based molecule, ACCG-2671, is a DACRA that is being evaluated for use either alone or in combination with GLP-1R agonists to treat obesity and associated diseases. ACCG-2671 is ...
--Structure Therapeutics Inc., a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic and pulmonary diseases, today announced the first ...