By understanding this "crosstalk" researchers expect to gain insights into autoimmune diseases such as multiple ... describes how cell surface receptors cooperate to generate immune responses ...

Nervous necrosis virus typically enters host cells via endocytosis, but it can also enter via a process called macropinocytosis.

G protein-coupled receptors (GPCRs ... GPCRs are membrane proteins on the cell's surface. There are approximately 800 different GPCR types, each of which can detect and bind specific molecules ...

To date, about 70 different Rab proteins have ... proteins can lead to a wide range of diseases, and receptors that never reach the cells surface can do the same. While Wu suspects the vesicles ...

1 Cell signaling receptors are proteins on the cell surface or inside the ... neurodegenerative disorders, and autoimmune diseases. There are different causes of signaling dysregulation.

Based on meta-analysis of over 100 studies of transmembrane cell-surface receptors ... Therefore, there are many different kinds of receptors. For example, humans have over a thousand encoded ...

Adenosine mediates its effects on inflammatory cells by engaging one or more cell-surface ... of adenosine receptors on different cell types change during the course of rheumatic diseases, such ...

Apparently, evolution has assured that ATP is indispensable inside cells, and as a signalling molecule between them. Figure 1: ATP signalling and families of mammalian ionotropic receptors.

By swapping out which cell surface receptors were targeted by the patch, the researchers showed that different cell types ... ways to treat COVID-19, heart disease, and diabetes, and perhaps ...

At Tau2020, a new conference held February 12 and13 in Washington, D.C., Ken Kosik, University of California, Santa Barbara, reported that tau slips into cultured human neurons by binding LDL-receptor ...

It also could lead to new, targeted therapies for other diseases. The breakthrough, described in Nature, revolves around engineered receptors on the surface ... one cell could affect different ...

Studies in mice show that these engineered cells can kill their targets without causing undue toxicity. Chimeric antigen receptor (CAR ... uPAR and tested them in several different mouse models of ...