T cells play an essential role defending the body against viruses and bacteria. To mount these defenses, T cells must sense these pathogens via cell surface receptors known as antigen receptors.

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo. The cells ...

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo.

Activation of transmembrane cell-surface receptors via a common mechanism? The “rotation model” . BioEssays , 2015; 37 (9): 959 DOI: 10.1002/bies.201500041 ...

Human cells sense and communicate via cell surface receptors on their surface. Information about the environment is relayed to the inside of the cell through dynamic changes in their arrangement ...

The UAB researchers showed that TREM2 — which stands for triggering receptors expressed on myeloid cells 2 — is predominantly ...

LRP1 belongs to the LDL receptor family (left). These, and more distantly related cell surface receptors (right), bind a wide range of proteins and play important roles in cholesterol metabolism, ...

Cell-surface receptors are the targets for more than 60% of current drugs. Traditionally, optimizing the interaction of lead molecules with the binding site for the endogenous agonist (orthosteric ...

The team claims the cell surface receptor, delta decorin (ΔDCN), is differentially expressed on ASCs, and has as its ligand resistin, an adipokine for which a receptor had not previously been ...

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T cells play an essential role defending the body against viruses and bacteria. To mount these defenses, T cells must sense these pathogens via cell surface receptors known as antigen receptors.