† Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States ‡ Department of Chemistry, Northwestern University, Evanston, Illinois 60208, United States Article Views ...

Figure 1 is a variant of a typical drug discovery/development flow chart adapted for antibiotics; 68 the low success rate emphasizes the importance of starting with molecular frameworks that can ...

Carbon monoxide (CO) is the simplest carbon oxide, an important industrial and laboratory chemical, and a deadly toxin. The molecular structure of CO is unusual. It is variously written with a ...

Ascentage Pharma is discovering and developing small molecule drugs for the treatment of cancer that block or degrade protein targets implicated in cancer. It has active clinical programs targeting ...

Key Laboratory of Molecular Nanostructure and Nanotechnology, Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Science, Beijing 100190, China University ...

“We were thrilled to find a small molecule that targets a killer protein called BAX and stops it working,” said co-corresponding author and the Head of WEHI’s New Medicine and Diagnostics ...

The team at WEHI, including researchers from the Parkinson's Disease Research Center, have identified a small molecule that can selectively block cell death. Published in Science Advances ...

This month we feature chemicals that have important applications in industry and the lab.—Ed. Calcium carbonate (CaCO 3) is a natural product found in many settings, including the minerals aragonite 1 ...