Sex-specific cardiovascular drug dosages are needed to reduce adverse reactions in women, ... director of the Cardiovascular Pharmacology Research Group, Universidad Complutense, ...

Sex-specific cardiovascular drug dosages are needed to reduce adverse reactions in women, according to a position paper from the European Society of Cardiology published today in the June issue of ...

Expert Rev Clin Pharmacol. 2010;3(3):321-329. Torsades de pointes (TdP) arrhythmia is a potentially life-threatening cardiac disorder that is often associated with a prolonged QT interval in the ...

Landmark trials have shown that GLP-1 receptor agonists, originally developed for diabetes and weight loss, also provide ...

The majority of drug interactions today are attributed to the cytochrome P450 (CYP450) isoenzyme system. However, new data suggest that transport proteins also play a key role. One such ...

Because these drugs given alone have been questioned for cardiac toxicity, the idea emerged for dual PPARα/γ activation by a single drug - the one piece of bait that in theory successfully lures ...

"Some drugs lengthen the QT interval and they are known to have this risk factor for an abnormal heart rhythm associated with sudden cardiac death." People at the greatest risk had a genetic ...

JUNE 10, 2025 — UTSA researchers in the Max and Minnie Tomerlin Voelcker CIDD Preclinical Pharmacology Core for Accelerated Drug Discovery were recently awarded a competitive grant that will allow ...

The blockbuster diabetes and weight loss drug semaglutide (Wegovy, Ozempic, Rybelsus) reduced the relative risk of heart attack, stroke, or cardiovascular deaths by 20 percent in high-risk ...

Expert Rev Clin Pharmacol. 2010;3(3):321-329. Despite a propensity to block hERG channel function, as determined by electrophysiology, for a limited number of compounds no cardiac arrhythmias have ...