“By combining two agents with mechanisms known to reduce [apnea ... Apnimed has its own carbonic anhydrase inhibitor for OSA. Last month, it acquired global rights to sulthiame from German ...

Carbonic anhydrase IX is a hypoxia-induced transmembrane enzyme ... that such ROCK1 mediated modulation of adhesion is a general and functionally important mechanism. We previously demonstrated that ...

Carbonic anhydrases (CAs; EC 4.2.1.1 ... their effects are organ-specific and the precise molecular mechanism remains elusive. It is likely that cytosolic CA isoforms are primarily involved, but it is ...

The un-linked polymers were mixed with photoinitiators and a solution of carbonic anhydrase and extruded through a fine nozzle with a syringe pump. The resulting thread was blasted with 280–450 ...

This may result from loss of sensitivity to the inhibitory effect of the drug by the carbonic anhydrase system or from local tubular or general metabolic adjustments. If the drug is given only ...

This deletion mutation, a type of mutation where a section of DNA is missing, not only explains the peculiarity of ginger genetics, but also reveals an entirely new mechanism for promoting orange ...

Carbonic anhydrase IX (CA IX), a transmembrane isoform with predominant association with tumors and limited distribution in normal tissues, is strongly overexpressed by hypoxia. Hypoxia increases the ...

Contribution from the Istituto di Biostrutture e Bioimmagini-CNR, via Mezzocannone 16, 80134 Naples, Italy, Dipartimento delle Scienze Biologiche-Sezione Biostrutture, University of Naples “Federico ...

The United Nations received permission from Israel for 93 more aid trucks to enter the Gaza Strip on Tuesday, a spokesperson for its humanitarian office and Israeli authorities said, as ...

Int Ophthalmol Clin. 2014;54(1):103-114. Topiramate is typically started at 25 mg daily and can be titrated up to 100 mg twice daily. It is frequently given in addition to acetazolamide in the ...