Alfred L. Garfall, MD, provided a deep dive into the phase 2 BMT CTN 1902 trial of ide-cel in multiple myeloma after ...

In developing this automated cell therapy processing platform, Limula’s founders aim to create a disruptive production ...

T-cell therapy has shown remarkable clinical efficacy in haematological malignancies, currently representing a well ...

TP53 mutations in AML confer resistance to CAR T-cell therapy through exhaustion of CAR T-cells, and dysregulation of the mevalonate and Wnt pathways in AML and CAR T-cells, respectively. Targeting ...

CHICAGO -- A single infusion of the chimeric antigen receptor (CAR) T-cell therapy ciltacabtagene autoleucel (cilta-cel; ...

Focus V has shown limited PFS benefit, a high incidence of AEs, and no demonstrated improvement in overall survival.

The early mammalian embryo and cell lines derived from it are characterized by distinct metabolic states that have long been assumed to be a byproduct of differentiation, and together they represent ...

The genetic manipulation of Paneth cells, their tracking and depletion depends on a solid Paneth cell specific Cre transgenic line. Here we describe bulk RNAseq-based expression data from pure, sorted ...

You take capecitabine as a tablet ... You should contact your advice line urgently if you think you have an infection. You might be breathless and look pale due to a drop in red blood cells. This is ...

To address this, researchers developed a "cell line atlas," which is a collection of cancer cell lines—each derived from an individual patient's tumor and adapted to grow in the lab—with ...