Scientists have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research. The increase in lifespan ...

Indeed, parasitic nematodes invade their hosts as infective larvae, a stage with striking morphological similarities to the dauer stage of C. elegans. The details of the signaling pathways ...

"Our evidence suggests that DAF-36 works early in a pathway ... the C. elegans reproductive capacity and prevent the organism from going into the immature long-lived larval phase called dauer ...

New research has uncovered how the body clears dying cells during times of stress, shedding light on the unexpected role of ...

In experiments with roundworms of the species Caenorhabditis elegans, researchers at the State University of Campinas (UNICAMP) in Brazil found that when this communication pathway is dysregulated ...

This worm, the C. elegans, is often used in aging research. Even though it’s biologically a long way from humans, it shares many genetic pathways with humans. “Nature doesn't waste basic cell ...

Figure 2: Role of insulin/IGF-1 and TGF-β pathways in controlling reproductive growth versus dauer development ... Figure 5: Structures of the C. elegans acyl-CoA oxidases ACOX-1.1 and ACOX ...

The work, done in the nematode worm C. elegans and detailed in ... cells and what were the molecular pathways involved that caused a worm to enter dauer. "The idea that a single gene mutation ...

Additionally, all components of the TGF-β Dauer signaling pathway are required ... further examined the physiological phenotypes of C. elegans with neuronal mitochondrial stress and observed ...

The nematode worm C. elegans is commonly used by neuroscientists to understand the nervous system. Scientists at Scripps Research in Florida used it in a new way to discover fresh insights about ...