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Key Points. Bleach can kill bed bugs on contact, but it's not enough to handle an infestation. You can spray visible bugs with a 50/50 bleach and water mix, but it won’t reach hidden ones.

Bed bug infestations usually occur around or near areas where people sleep, the CDC said. Bed bugs can travel over 100 feet in a single night, but tend to live within 8 feet of where you sleep.