Methods APRIL and BAFF gene expression was assessed in published transcriptional datasets from healthy donors and SLE patients. PBMCs from healthy donors were stimulated with CD40L, IL-21, BAFF, and ...

Objective To evaluate the efficacy and safety of tabalumab, a monoclonal antibody that neutralises membrane-bound and soluble B-cell activating factor (BAFF), in patients with active rheumatoid ...