Alnylam and BridgeBio are competing for people who are switching from Pfizer’s blockbuster ATTR amyloidosis drug tafamidis while all three companies are fighting for new patients.

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

In conclusion, in addition to cAMP-related mechanisms, the renal vasodilator effects of AM may be exerted via release of NO. Although synthesis and secretion of AM have not yet been demonstrated in ...

The framework approved by the government enables businesses, industries, and organizations-particularly those not covered under the compliance mechanism-to participate in climate action and receive ...

The mechanism of action of baxdrostat involves inhibiting the enzyme aldosterone synthase, which is responsible for the final step in aldosterone biosynthesis. By selectively blocking this enzyme ...

There still is a high unmet need. With this approval, we'll have a unique mechanism of action. We'll have another treatment option [with] reduced resistance due to its mechanism of action, and I think ...

This trial, conducted by neuroscientists at the University of Texas at Austin and published in Biological Psychiatry Global Open Science, adds to the growing body of evidence supporting Deprexis’ ...

Glioma Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.

Penicillins are a subclass of antibiotics (called beta-lactams) that are used to treat illnesses, including streptococcal infections (caused by gram-positive bacteria) and meningococcal infections ...