The finding that basophil counts may have prognostic significance aligns with a growing body of research into basophils in ...

Chemoattractant-stimulated granule release from neutrophils, basophils and eosinophils is critical for the innate immune response against infectious bacteria. Interleukin 8 (IL-8) activation of ...

DCs interact with different immune cells to dictate the immune response. This interaction may be direct (T-cells), or indirect (with B-cells, eosinophils, neutrophils, mast cells and basophils ...

Current guidelines suggest limiting diagnostic testing for chronic spontaneous urticaria when no clear cause is suspected, though biomarkers and biopsies are emerging as tools to predict treatment ...

Eosinophils contribute to the pathophysiology of allergic symptoms by release of cysteinyl leukotrienes (Cyst-LTs), which are also produced by mast cells and basophils.

With just a 50-µL blood sample well mixed in a lavender top, K2 EDTA tube (Greiner Bio-One Minicollect Tubes, Ref#450480), this machine provides the cell number (109/L) and percentages for lymphocytes ...

Blood and plasma histamine levels, together with circulating basophil and eosinophil counts, were estimated in a group of asthmatic children. Short-term studies were carried out on 7 patients, each of ...

The Lancet on the anti-IL-5 antibody mepolizumab in individuals with allergic asthma, evidence has accumulated that the pathogenetic role of eosinophils is fundamentally different between asthma ...

The innate leukocytes include NK cells, mast cells, eosinophils, basophils and the phagocytic cells, including macrophages, neutrophils and dendritic cells.

Novartis builds case for Xolair follow-up ligelizumab in chronic spontaneous urticaria or CSU, as phase 3 trials head for data readouts later this year ...

NEUTROPHILS, MAST CELLS, BASOPHILS AND EOSINOPHILS IN LUNG DISEASE. Ward JR, West PW, Ariaans MP, Parker LC, Francis SE, Crossman DC, Sabroe I & Wilson HL (2010) Temporal interleukin-1beta secretion ...

4.2 Targeted treatment of eosinophils and basophils As previously discussed, some cytokines (IL-5, IL-4, IL-13, and IL-31) and complement factors (C5a and C3a) play crucial roles in the pathogenesis ...