The finding that basophil counts may have prognostic significance aligns with a growing body of research into basophils in ...

Intranasal delivery of a monoclonal IgG1 antibody targeting mugwort pollen protected mice from allergic rhinitis and asthma ...

Etokimab (I-Mab Biopharma), which is optimized for common IL-33 gene polymorphisms, has completed patient recruitment in its Phase II trial. The strategic combination of IL-33 inhibitors with ...

Chemoattractant-stimulated granule release from neutrophils, basophils and eosinophils is critical for the innate immune response against infectious bacteria. Interleukin 8 (IL-8) activation of ...

DCs interact with different immune cells to dictate the immune response. This interaction may be direct (T-cells), or indirect (with B-cells, eosinophils, neutrophils, mast cells and basophils ...

Current guidelines suggest limiting diagnostic testing for chronic spontaneous urticaria when no clear cause is suspected, though biomarkers and biopsies are emerging as tools to predict treatment ...

Eosinophils contribute to the pathophysiology of allergic symptoms by release of cysteinyl leukotrienes (Cyst-LTs), which are also produced by mast cells and basophils.

With just a 50-µL blood sample well mixed in a lavender top, K2 EDTA tube (Greiner Bio-One Minicollect Tubes, Ref#450480), this machine provides the cell number (109/L) and percentages for lymphocytes ...

Blood and plasma histamine levels, together with circulating basophil and eosinophil counts, were estimated in a group of asthmatic children. Short-term studies were carried out on 7 patients, each of ...

The Lancet on the anti-IL-5 antibody mepolizumab in individuals with allergic asthma, evidence has accumulated that the pathogenetic role of eosinophils is fundamentally different between asthma ...

The innate leukocytes include NK cells, mast cells, eosinophils, basophils and the phagocytic cells, including macrophages, neutrophils and dendritic cells.

Novartis builds case for Xolair follow-up ligelizumab in chronic spontaneous urticaria or CSU, as phase 3 trials head for data readouts later this year ...