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Antibodies are proteins with around 150 kDa molecular weight. They have a similar basic structure comprising of four polypeptide chains held together by disulfide bonds. These four polypeptide ...
However, the basic chemical structure of antibodies had been already determined during the previous decade, in particular thanks to the works of Rodney Porter and Gerald Edelman.
Structural biologists at Fred Hutch have created 3D images that show how a potent antibody from a COVID-19 survivor interferes with a key feature on the surface of the coronavirus’s distinctive spikes ...
The article, "The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function," was published in Nature Communications.
The structure of HSV-1 gB in complex with D48 Fab and structural and sequence comparison with HCMV and EBV gB with their neutralization antibody reveal DII as a conservative antigenic domain ...
Antibodies, also known as Immunoglobulins, are incredibly specific molecules that bind to their target antigen and neutralize it in the most common cases.
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